Bidirectional association of neurodevelopment with growth: a prospective cohort study

Abstract Background The study aims to use the cross-lagged model and utilize data from Born in Shenyang Cohort Study characterize bidirectional associations of term-born infants’ neurodevelopment five domains physical growth early life. Method This consists 688 mother-child dyads Study. Infants’ anthropometric (weight length) development neurological outcomes (Gesell Development Scale) were measured at age 6 12 months. Cross-lagged analyses multiple linear regression used explore longitudinal relationships both directions. Results In terms studies, inverse between two skills (gross motor social behavior) months with BMI Z -scores motor: a? = ? 0.20, 95% CI: 0.31 to- 0.09; behavior: 0.23, 0.33 0.13) found. Conversely, a higher infant -scored predicted lower gross (a? 0.08, 0.12 0.04). analyses, an adverse association directions was observed. Conclusion We found suggested infants, who are on edge developmental danger, should not be overlooked.